Vol. 9, Special Issue 1, Part N (2025)

At the age of 20 days, two Pulikulam cattle female calves were exhibited anorectic, haemorrhagic diarrhoea, tenesmus, poor coat condition and in sternal recumbency in a Pulikulam cattle herd during July 2024. The study was carried out to find the cause to make effective therapeutic management and hematological changes in whole blood samples. The dung samples examination under microscope revealed that the presence of Eimeria species oocyst in both samples. Based on the findings, the calves were treated with Sulphadiazine and Trimethoprim @ 30 mg per kg body weight with supportive therapy including Vitamin A-one ml intramuscularly, Dextrose Normal Saline @ 20 ml per kg body weight and Ringers Lactate @ 15 ml per kg body weight intravenously for intestinal mucosal regeneration, to correct the dehydration and electrolyte imbalances. The calves were administered the medication for 5 days and the calves were recovered fully with confirmation of the absence of Eimeria oocyst in the dung samples on 6^th day of the treatment. The reduction of erythrocytes, hemoglobulin, Packed Cell Volume and elevated leukocytes in the infected animals revealed that those affected had with internal hemorrhage and secondary bacterial infection. The moist and warm environment might predispose for the occurrence of coccidiosis in Pulikulam cattle calves and the parenteral administration of Sulphadiazine and Trimethoprim was very effective against coccidiosis in calves.