Vol. 9, Special Issue 11, Part G (2025)

Marine ecosystems are a rich source of microbial diversity with potential bioactive compounds compared to non-marine, including bacteriocins natural antimicrobial peptides with applications in food preservation and pharmaceuticals. The marine bacteria were isolated from coastal seawater samples, identified using morphological, biochemical, and molecular approaches, and screened for bacteriocin production. In the present study, marine bacterial strains were isolated from coastal seawater samples collected from different sites to explore their bacteriocin-producing potential. The isolates were subjected to morphological characterization such as colony morphology, Gram staining, and motility. The biochemical assays such as catalase, oxidase, carbohydrate fermentation tests and molecular identification using 16S rRNA gene sequencing were done. The selected strains were characterized, and bacteriocins were extracted and evaluated for antimicrobial activity against foodborne pathogens. The results demonstrated that several marine bacterial isolates exhibited significant inhibition zones against Listeria monocytogenes, Staphylococcus aureus, and Escherichia coli, suggesting their potential for application in antimicrobial formulations.