Vol. 8, Special Issue 7, Part L (2024)

Abstract: The study was undertaken to estimate the levels of thyroid hormones and lipid profile and their correlation with stages of lactation in Murrah buffalo. Blood samples were collected twice at month interval from 24 healthy lactating Murrah buffaloes during early, mid and late stages of lactation. There was significant increase in the levels of total triiodothyronine (TT₃) during late stage of lactation. However, the levels remained almost same during the early and mid-lactation. total thyroxine (TT₄) levels remained same during early and late stage of lactation, but the levels decreased significantly during mid-lactation stage. There were significant changes in the levels of free T4 during mid lactational stages. All the lipid profile parameters viz. Triglycerides, Total Cholesterol, HDL-c, LDL-c and VLDL-c have shown significant increased (p< 0.005) during mid-lactation. The higher level of cholesterol and triglycerides with advancement of lactation may be the physiological adjustment to meet the lactation requirement for lactogenesis. Barring HDL-cholesterol thyroxine and free thyroxine hormone in serum was negatively correlated with total cholesterol, triglyceride, LDL cholesterol, VLDL cholesterol. However, all the relation were statistically no significant.