Author(s): Sanjay Kumar Yadav, Sikhamoni Haloi, Raju Sharda, Mahmuda Malik, Chhote Lal Yadava and Chandra Prakash Dixit

Abstract: Twenty-four Wistar rats were used in the study to assess Cissus quadrangularis impact on the healing of long bone fractures. The animals were split into four equal groups, Groups I, II, III, and IV, with six animals in each group, at random. Rats in Group I were maintained as a healthy control, rats in Group II were maintained as an operative control, rats in Group III were treated with Cissus quadrangularis (CQ) P.O. 400 mg/kg body weight daily for 30 days, and rats in Group IV were treated with tropical application of Cissus quadrangularis (CQ) on site daily for 30 days. Assessments were made of the haematological parameters. Haematological parameters experienced brief variations that stayed within typical physiological ranges. Compared to other groups, the animals in Group III that received oral administration of Cissus quadrangularis saw early recovery of their damaged bones. Since it took a little longer, topical treatment of Cissus quadrangularis (group IV) was carried out. Nevertheless, compared to group II (surgical control), which received no treatment, groups III and IV both performed better. It follows that Cissus quadrangularis promotes early, prolonged bone fracture repair.

DOI: 10.33545/26174693.2024.v8.i4Se.996