Author(s): Ravina, Dharamshaw CA, Pallavi Rathi, Chandana Sree Chinnareddyvari, Rangasai Chandra Goli, Kiyevi G Chishi and Gaurav Patel

Abstract: The study conducted in Garole sheep aimed to identify genome-wide single nucleotide polymorphisms (SNPs) and annotate them to various production traits. Using Illumina OvineSNP50v1 genotyping data from 26 Garole sheep samples, a total of 46,820 high-quality SNPs were identified after rigorous quality control measures. Annotation of these SNPs revealed 760 SNPs associated with 175 candidate genes implicated in milk production traits, including genes regulating fatty acid oxidation, milk yield, and energy metabolism. Notable candidate genes identified included Acetyl-CoA carboxylase Beta (ACACB), Growth hormone receptor (GHR), and Leptin (LEP). This analysis provides valuable insights into the genetic architecture of Garole sheep, highlighting the potential for targeted breeding programs aimed at improving economically important traits such as milk yield and composition. Understanding the genetic basis of these traits is crucial for designing effective breed improvement strategies and enhancing overall productivity in Garole sheep.

DOI: 10.33545/26174693.2024.v8.i3Sd.724