Squamous cell carcinoma is a prevalent malignant tumor found in various domestic animals, primarily affecting the non-pigmented areas of the skin. In dogs, this type of cancer commonly occurs in the skin (cutaneous), mouth (oral), or nailbeds (subungual). A four-year old dog was brought in with a growth located in the femur region of its leg. Upon examination, a raised, whitish pink mass resembling a cauliflower was observed in the femur region of the left leg. The growth was surgically removed, and tissue samples were collected for histopathological analysis. Under the microscope, the biopsy revealed the presence of neoplastic squamous cells arranged in islands, cords, and trabeculae. Some of these islands exhibited keratin pearls, indicating differentiation. Based on the histopathological features, the case was conclusively diagnosed as squamous cell carcinoma in a dog.