Author(s): Esha Sinha, Khushboo Panwar, Priyanshi Yadav, Bhavani Puvvala, Shikha Bishnoi and Krishna J Patel

Abstract: The primary objective of this study was to investigate the antimicrobial resistance patterns of Escherichia coli (E. coli) isolated from wound infections in animals, particularly focusing on samples obtained from dogs. The confirmation of E. coli was carried out through comprehensive cultural and biochemical characterization of both pus and wound samples. A total of 20 samples, encompassing various wound and skin afflictions, were collected from dogs, irrespective of gender and age. Upon isolation, 20 distinct E. coli isolates were identified and subjected to antibiotic sensitivity testing using a panel of nine commonly used antibiotics. The results of the sensitivity tests revealed varying degrees of susceptibility among the isolates. Notably, the isolates exhibited maximum sensitivity to Amoxicillin, with a rate of 70%. Following closely, Ciprofloxacin demonstrated a sensitivity rate of 65%, while Erythromycin displayed the least sensitivity at 25%. In contrast, the isolates demonstrated heightened resistance to certain antibiotics. Specifically, Penicillin and Gentamicin elicited the highest resistance rates, both standing at 70% and 65%, respectively. Conversely, the isolates displayed minimal resistance to Ciprofloxacin and Co-Trimoxazole, each registering a low resistance rate of 4%. These findings provide valuable insights into the antibiotic resistance landscape of E. coli strains isolated from canine wound infections, emphasizing the importance of understanding and monitoring antimicrobial resistance in the context of veterinary medicine.

DOI: 10.33545/26174693.2024.v8.i1Sh.435