Vol. 8, Special Issue 12, Part A (2024)
One-pot synthesis of bimetallic Cu/ZnO nanoparticles using tea leaves (Camellia sinensis) for anticancer applications
Aryaman Kejriwal
Nanoparticles are extensively researched across various domains for their unique attributes and broad application potential, with bimetallic nanoparticles receiving particular focus due to their superior catalytic activities and stability over monometallic types. Traditional methods for synthesizing bimetallic nanoparticles often rely on toxic reducing agents, are energy-intensive, and require multiple procedural steps, underscoring the need for more sustainable and straightforward approaches. This study introduces a one-pot synthesis strategy for creating bimetallic copper/zinc oxide nanoparticles (Cu/ZnO NPs) using Camellia sinensis (Tea leaves) as a natural reducing and capping agent. This method is eco-friendly and cost-effective, aiming to overcome the drawbacks of conventional synthesis techniques. The nanoparticles produced were thoroughly analysed using scanning electron microscopy (SEM), transmission electron microscopy (TEM), UV-visible spectroscopy (UV-Vis), and X-ray diffraction (XRD), confirming the successful formation of bimetallic nanoparticles.
The Cu/ZnO nanoparticles exhibited a consistent particle size of about 6 to 8 nm. UV-Vis spectroscopy helped elucidate their optical properties, affirming their bimetallic composition. SEM and TEM investigations showed the nanoparticles' spherical shape and crystalline structure. These nanoparticles demonstrated significant biological activity, with a 91% effectiveness in inhibiting cancer cell growth, highlighting their potential in anticancer applications. They also displayed notable antimicrobial properties, enhancing their applicability in a wider range of biomedical contexts. Overall, this green synthesis route not only provides a viable alternative for producing bimetallic nanoparticles but also expands their possible uses in medical treatments and devices.
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