Vol. 9, Issue 9, Part D (2025)

Samples of pineal gland were collected from pre and postnatal groups of sheep. Pineal gland in sheep was a small white, round shaped structure located between the thalamus and corpora quadrigemina of the brain. In group I, it consisted of pinealocytes. In group II, pinealocytes and a few glial cells were observed. In group III and IV outer cortex and inner medulla regions were observed. From group V and VI, cells of the cortex and medulla were reduced and vacuolated spaces increased. A moderate PAS positive and alkaline phosphatase positive activities were observed in pinealocytes of all groups. A weak Millon’s, reaction and acid phosphatase positive reaction were identified in the pinealocytes. A strong positive alpha naphthyl acetate esterase reactions were noticed in the pinealocytes of all groups studied.