Vol. 9, Issue 8, Part C (2025)

In the present study, 30 broiler chicks were randomly divided into two equal groups (Gr I and Gr II). Gr I chicks received drinking water (fluoride conc 0.9 ppm) and standard broiler starter (up to 3 weeks of age) and finisher ration (mean fluoride concentration 4.7 and 4.5 ppm, respectively) to serve as negative control, while Gr II received water containing 400 ppm fluoride and feed similar to Gr I. Body weight was measured and blood samples were collected on day 0, 20 and 40 of the experiment. On day 20, the mean body weight of Gr II chicks was 4.32% lower, while on day 40, it was 7.49% lower in comparison to Gr I. Hemoglobin concentrations in Gr II on day 20 and 40 were significantly (p<0.05) lower than corresponding values in Gr I. RBC count and PCV were also lower, but WBC counts were higher in Gr II in comparison to corresponding values in Gr I. Furthermore, significant increase in aspartate aminotransferase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), creatinine and urea nitrogen were recorded in Gr II on day 40. Results suggested that excess fluoride (400 ppm or more) exposure in chick have suppressive effects on growth rate and erythropoiesis, increase in leukocyte count and level of enzymes related to liver and kidney functions.