Vol. 9, Issue 2, Part C (2025)

Abstract: Various measures are being taken to check the uncontrollable increase in human population over the decades, devising various contraceptive methods is one of them. Quinestrol (synthetic estrogen) is used in formulation of many contraceptive pills. These hormonal pills have a very high success rate if used as prescribed. Present study was formulated to evaluate the effect of quinestrol on biochemical markers in female albino rats. Female albino rats were treated with 2 mg/kg body weight of quinestrol for a period of 10 days. Quinestrol treatment showed no significant effect on the body weight and organ weight of treated rats. However, uterus of all the treated rats showed severe oedema. Biochemical markers performed on rat ovarian tissue homogenate showed significant decrease in total lipid content, phospholipid content and total soluble proteins. Whereas, cholesterol levels increased significantly.