Vol. 9, Issue 2, Part C (2025)

This work aims to evaluate the potential for Arundo donax root extract, which is well known as an ingredient of traditional Chinese as well as indian medicine, to prevent diabetes and to compare the results with the commonly-used prescription medicines. In a series of in vitro assays the extract has shown pronounced inhibitory activity against α-amylase and α-glucosidase with the calculated IC₅₀ values of 10 µg/ml and >9 µg/μl, respectively, which indicates that the investigated extract has the potential for an effective treatment of type 2 diabetes. Moreover, the DPPH assay of the extract yielded a feeble radical scavenging activity of 57.28% at a concentration of 10µg/ml which shows that the extract has good antioxidant potential than that of ascorbic acid.. Altogether, these data indicate the feasibility of Arundo donax root extract in anti-diabetic activity considering the area of traditional Indian medicine. Subsequent studies are required to better understand how it works and to confirm its potential uses in treatment.