Vol. 9, Issue 12, Part I (2025)

Neoplasms in animals and humans occur when cells with altered DNA begin to grow uncontrollably. The term neoplasm originates from the Greek words neo and plasma, meaning new growth. This uncontrolled growth can form a tumour and may be either benign (non-cancerous) or malignant (cancerous). These abnormal cells divide continuously, pushing out and replacing healthy tissues. Different tumours noticed in dogs are mammary tumors, basal cell carcinoma, mast cell tumors, lipoma, hemangioma, hemangiosarcoma, fibroma, fibrosarcoma and many more. Mammary tumours are the most commonly detected tumour in intact female dogs and also seen in some male dogs and it remains a major cause of mortality. Dogs naturally develop mammary tumors that exhibit many biological, clinical, pathological, and molecular similarities to human breast cancer. Mammary tumours have been reported as the most frequently occurring type after skin tumours. The standard treatment for tumors in dogs begins with surgery as the primary option, and may be supplemented with chemotherapy, radiation therapy, immunotherapy, cryotherapy, hyperthermia, and hormone based treatments depending on the type and nature of the tumours. So the present study was conducted in six clinical cases, all the dogs were estimated for different haemato-biochemical parameters before surgery followed by 14^th and 45^th day post surgery. All the dogs were subjected for surgical excision of tumors under balanced general anaesthesia and the samples were subjected for histopathological examination. Based on the histopathological findings the tumours were diagnosed as different types of benign and malignant tumours.