Vol. 9, Issue 12, Part H (2025)

This clinical study evaluated biochemical markers of fracture healing in dogs treated with Point Contact Fixator (PC-Fix) and Locking Compression Plate (LCP) systems. Twelve dogs with femoral or tibial diaphyseal fractures were randomly assigned to two groups: Group I treated with PC-Fix and Group II treated with LCP. Serum alkaline phosphatase, serum calcium and serum phosphorus levels were measured pre-operatively and on post-operative days 0, 15, 30, 45 and 60. Alkaline phosphatase was highest pre-operatively, declined by day 30 and showed a slight increase by day 60, reflecting osteoblastic activity. Calcium and phosphorus concentrations increased steadily until day 30, then declined, indicating active bone remodelling and mineral metabolism. All values remained within physiological limits. Both implant systems demonstrated effective stabilization and comparable biochemical healing profiles, with PC-Fix showing slightly earlier functional recovery. These findings highlight the utility of biochemical markers in monitoring fracture healing and affirm the clinical viability of both implant systems in canine orthopaedics.