Vol. 9, Issue 11, Part E (2025)

A six-year old female dog is presented with an enlarged abdomen, showing restlessness, vomiting, polyuria, polydipsia, with decreased appetite. The physical examination revealed yellowish to brownish purulent vaginal discharge with an unpleasant smell. Hematology result revealed hypochromic, normocytic anemia, including an elevated level of alkaline phosphatase. Diagnosis of pyometra based on history, physical examination, hematology, biochemical tests and ultrasonography of the abdomen, it was concluded that the female dog was diagnosed with open cervix pyometra. Based on the following examination, an ovariohysterectomy was performed. The Patient treated with Ampicillin-cloxacillin (Injection Megapen® 500 mg) antibiotics were administered intramuscularly at a dose @ 15 mg/kg of body weight, for 7 days thrice a day, tablet pantoprazole 40 mg empty stomach to reduce the amount of acid production in stomach, Darbepoetin alfa (Cresp^®40 mcg, 0.4 ml S/C-super-sialylated analog of human erythropoietin) injection causes the bone marrow to produce red blood cells to treat low hemoglobin and RBC count, Supportive therapy: Vitamin-B complex (Injection Tribivet, 2.5 ml for 7 days) and Pronefra® palatable oral suspension.