Vol. 9, Issue 11, Part C (2025)

The present study aimed to determine the antibiotic susceptibility pattern of Staphylococcus aureus isolates recovered from poultry meat using the disc diffusion method. A total of 46 S. aureus isolates were subjected to antibiotic sensitivity testing against ten commonly used antibiotics following the Clinical and Laboratory Standards Institute (CLSI) guidelines. The results revealed the highest resistance to oxacillin (65.22%) and chloramphenicol (60.87%), followed by moderate resistance to levofloxacin (23.91%). Low resistance was noted for amikacin (13.04%) and trimethoprim (10.87%), while all isolates were completely susceptible to ciprofloxacin. Gentamicin exhibited the highest sensitivity (93.48%), followed by doxycycline hydrochloride (76.09%). The overall antibiogram indicated a predominance of multidrug-resistant S. aureus strains in poultry meat, posing potential risks to public health. The observed resistance trends were in agreement with several previous reports, reflecting the growing concern of antimicrobial resistance in foodborne pathogens.