Vol. 8, Issue 8, Part O (2024)
Potential of silk fibroin in biomedical science
Author(s):
Jasmeena Qadir, Shalini Aryan, Somagaini Pavankumar and Sumiya Afreen
Abstract:
Silk fibroin is a natural biopolymer produced by many sericigenous insects viz., silkworms and spiders. Owing to its remarkable biological and mechanical attributes employs its wider utilization in biomedical science in addition to textiles. The efficient biocompatibility, biodegradation, unique mechanical features makes it a facile stuff effective for tissue regeneration, tissue engineering’s and small molecular and drug deliveries. Silk fibroin have been designed in various models viz., silk films, silk hydro-gels, silk 3-dimensional porous scaffolds, non-woven scaffolds, particles, silk fibers or silk composites for exploring their functionalization in different biomedical approaches. The fabrication of ideals designs of Silk fibroin biomaterials have been devised to improve the functional integrity and physiological relevance in tissue engineering techniques. These innovative SF tools represent absolute solutions for different clinical problems of tissues, bones, cartilage, heart, vascular system, nerves and skin regeneration. SF has been developed as an efficient drug and small molecular carrier/ vehicle for treatment of dreadful and challenging clinical problems like cancer. The current review discusses the topics pertaining to characteristics of silk fibroin and SF based biomaterials developed and evaluated for wider utilization in biomedical treatment of cardiac, neuron, skin, bone, liver and tooth related problems. The emphasis has been laid on perpetual use of effective silk fibroin based materials in future biomedical clinical care.
Pages: 1179-1190 | 319 Views 124 Downloads
How to cite this article:
Jasmeena Qadir, Shalini Aryan, Somagaini Pavankumar and Sumiya Afreen. Potential of silk fibroin in biomedical science. Int. J. Adv. Biochem. Res. 2024;8(8):1179-1190. DOI: 10.33545/26174693.2024.v8.i8o.1947