International Journal of Advanced Biochemistry Research

Biochem
Journal

Printed Journal   |   Indexed Journal   |   Refereed Journal   |   Peer Reviewed Journal

Vol. 8, Special Issue 6, Part A (2024)

In vitro anthelmintic activity of aqueous extracts of seven medicinal plants against Haemonchus contortus in goats

Author(s): Dr. Ramakant, Dr. Tarun Kumar Sarkar, Dr. Amit Kumar Verma, Dr. Prem Sagar Maurya, Dr. Vipul Thakur, Dr. Arbind Singh, Dr. Vikash Jaiswal, Dr. Shriya Rawat, Dr. Pankaj Kumar Maurya and Dr. Sachin Gautam
Abstract: The aim of this study was to evaluate the In vitro anthelmintic efficacy of aqueous extracts from various plants against Haemonchus contortus in goats. The selected plants included of Coriandrum sativum seeds, Allium sativum bulb, Carica papaya seeds, Zingiber officinale rhizome, Azadirachta indica leaves, and Swertia chirata whole plant and Prunus persica leaves. For this purpose, an adult worm mortality assay was conducted using adult Haemonchus contortus worms collected from the abomasum of naturally infected goats. Adult mature parasites of Haemonchus contortus were collected from abomasum of naturally infected goats. Adequate amount of plant materials were collected. The collected plant materials were cleaned, dried under shade and then used to prepare aqueous extracts. In In vitro study, four concentrations of the aqueous extracts (50 mg/ml, 100 mg/ml, 200 mg/ml, and 400 mg/ml) were tested at regular time intervals, and viability of parasites was recorded over an 8 hours periods. Closantel (at the concentration of 1.25 mg/ml) and PBS were used as the positive and negative controls, respectively. The results showed that aqueous extracts of Swertia chirata whole plant of exhibited the highest adulticidal effects followed by Coriandrum sativum seeds, Azadirachta indica leaves, Allium sativum bulbs, Carica papaya seeds, Zingiber officinale rhizome and lowest in Prunus persica leaves against the Haemonchus contortus in goats. This indicates that these plant extracts have potential anthelmintic effects.
Pages: 51-58  |  112 Views  62 Downloads


International Journal of Advanced Biochemistry Research
How to cite this article:
Dr. Ramakant, Dr. Tarun Kumar Sarkar, Dr. Amit Kumar Verma, Dr. Prem Sagar Maurya, Dr. Vipul Thakur, Dr. Arbind Singh, Dr. Vikash Jaiswal, Dr. Shriya Rawat, Dr. Pankaj Kumar Maurya, Dr. Sachin Gautam. In vitro anthelmintic activity of aqueous extracts of seven medicinal plants against Haemonchus contortus in goats. Int J Adv Biochem Res 2024;8(6S):51-58. DOI: 10.33545/26174693.2024.v8.i6Sa.1254
International Journal of Advanced Biochemistry Research
Call for book chapter