International Journal of Advanced Biochemistry Research

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Vol. 8, Special Issue 3, Part H (2024)

Effect of silymarin and selenium-yeast supplementation on liver functions of Barbari goat during cold stress

Author(s): Pankaj Kumar Maurya, Rakesh Kumar Singh, Gulab Chandra, Prabhakar Kumar, Debashis Roy, Ahmad Fahim, Ramakant, Sachin Gautam and Mahendra Kumar Singh
Abstract: The aim of the present study was to assess the effect of silymarin (SM) and selenium-yeast (SY) on renal and hepatic functions of Barbari goat during cold stress. Thirty two Barbari goats (age: 6-8 months) were selected from ILFC- II, SVPUAT, Meerut, Uttar Pradesh, India. The animals were randomly divided into four groups (n=8) according to body weight and age. First group (C) was kept as control group giving only basal diet, second group (T1) supplemented with 600 mg Silymarin/kg DM/day, third group (T2) supplemented with 0.3 mg Selenium as Se-Yeast/kg DM/day and fourth group (T3) supplemented with 600 mg Silymarin + 0.3 mg Selenium as Se-Yeast/kg DM/day along with basal diet for 90 days of experimental periods. Supplementation significantly (p<0.05) influenced the level of plasma ALT, AST and ALP in the animals. The mean activity of plasma ALT, AST and ALP was found significantly (p<0.05) lower in T1, T2 and T3 groups as compare to control group. Mean daily weight gain (DWG) of the supplemented group was found significantly (p<0.01) more than control group. Dry matter intake (DMI) was found significantly (p<0.01) higher in supplemented group as compare to control group. The result of this study indicated that supplementation of SM alone and in combination with SY improves liver function by reducing liver enzymes and increasing feed intake in the Barbari goats during cold stress.
Pages: 619-623  |  157 Views  34 Downloads


International Journal of Advanced Biochemistry Research
How to cite this article:
Pankaj Kumar Maurya, Rakesh Kumar Singh, Gulab Chandra, Prabhakar Kumar, Debashis Roy, Ahmad Fahim, Ramakant, Sachin Gautam, Mahendra Kumar Singh. Effect of silymarin and selenium-yeast supplementation on liver functions of Barbari goat during cold stress. Int J Adv Biochem Res 2024;8(3S):619-623. DOI: 10.33545/26174693.2024.v8.i3Sh.830
International Journal of Advanced Biochemistry Research
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