International Journal of Advanced Biochemistry Research

Biochem
Journal

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Vol. 8, Issue 1, Part C (2024)

Cytopathological and histopathological study on canine fibrosarcoma

Author(s): Sunil Kumar Jangid, Ashok Prajapat, Sarjna Meena, Shashi Choudhary Naveen Kumar, Ram Kumar Gahlot and Neelam Kumari Faran
Abstract: Fibrosarcoma is a relatively uncommon yet alarming canine cancer that predominantly affects the dog's connective tissues. Its aggressive nature and the difficulties in treating it, fibrosarcoma diagnosis can be upsetting for dog owners. In contemporary Veterinary practice, Cytology especially Fine-needle aspiration cytology (FNAC) and impression smears are frequently employed methods for prompt diagnosis of neoplasms. This research aimed to determine the incidence, gross morphological, cytological and histopathological characteristics of Fibrosarcoma. So, in current investigation, tumours were diagnosed using both cytological and histopathological approaches. FNAC and impression smears were utilized for diagnosing palpable and non-palpable tumour masses from diverse dog breeds. Within this study, 58 cases of tumours were scrutinized and three instances of fibrosarcoma were analyzed. Grossly, varying sizes of the tumor masses, displayed an oval to irregular shape and a firm consistency. The cut surfaces exhibited a whitish-red appearance. The cytological smears unveiled the presence of pleomorphic fibrocytes, exhibiting spindle-shaped to plump forms, prominent nuclei with multiple nucleoli, coarse chromatin, and mitotic activity. The histological examination revealed characteristic features such as keratinization, a typical "whorling" pattern, round to oval nuclei with one or more prominent nucleoli, the presence of giant cells, anisokaryosis, and mitotic figures. These findings underscore the potential for cytology to become a more reliable and valuable diagnostic tool for assessing cutaneous and subcutaneous masses in small animal practice.
Pages: 193-196  |  194 Views  102 Downloads


International Journal of Advanced Biochemistry Research
How to cite this article:
Sunil Kumar Jangid, Ashok Prajapat, Sarjna Meena, Shashi Choudhary Naveen Kumar, Ram Kumar Gahlot, Neelam Kumari Faran. Cytopathological and histopathological study on canine fibrosarcoma. Int J Adv Biochem Res 2024;8(1):193-196. DOI: 10.33545/26174693.2024.v8.i1c.345
International Journal of Advanced Biochemistry Research
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