Background: A chronic kidney disease (CKD) is a kind of renal disease in which there is a gradual loss of renal function. Initially, CKD is described as renal insufficiency or reduced renal reserve, which may progress to renal failure.

Objectives: The present study aimed to assess the lipid profile among CKD patients attending a rural teaching hospital.

Materials and Methods: This prospective observational study was conducted at Tertiary care Hospital Sangareddy. A total of 100 study subjects were selected from MNR hospital during the period from June 2021 to December 2021. The sample size was calculated by open Epi software.

Results: Significantly higher levels of triglycerides, total cholesterol, low-density lipoprotein, and VLDL were estimated in CKD patients in comparison with controls (p<0.001). Significant lower mean HDL was seen in CKD patients.

Conclusion: Dyslipidaemia is found common among patients with CKD. Proper medication and lifestyle changes can reduce mortality in CKD patients. Finally, regular assessment of lipid profiles among CKD patients can prevent further complications.