Plasma cell dyscrasias with complete loss of immunoglobulin heavy chain expression: A rare case
Author(s): Garima Chauhan and Bijita Dutta
Background: We are presenting a cases of the monoclonal plasma cell proliferative disorders with complete loss of immunoglobulin heavy chain (HC) expression, which is not LC-MGUS.
Method: Many literatures and text books were being reviewed regarding the classification, presentation and annual progression rate of Light chain myeloma and other dyscrasias expressing only light chain.
Result: Literature data is very scarce. Most of the literatures are batting around LC-MGUS, but not beyond that.
Conclusions: More light should be thrown on this darker area of light chain expressing plasma cell dyscrasias for better management.
Garima Chauhan, Bijita Dutta. Plasma cell dyscrasias with complete loss of immunoglobulin heavy chain expression: A rare case. Int J Adv Biochem Res 2022;6(2):101-103. DOI: 10.33545/26174693.2022.v6.i2b.143