International Journal of Advanced Biochemistry Research
Vol. 5, Issue 1, Part A (2021)
Comparative study of HbA1c and superoxide dismutase in type II diabetes mellitus in Jalgaon district
Author(s): Pravin Kumar Sonawane, SB Gaikwad, Anshula G and Banker M
Abstract: Type II diabetes, formerly known as adult-onset diabetes, is a type of diabetes that is characterized by high blood sugar, insulin resistance, and relative lack of insulin due to obesity, lack of exercise or genetically determined. HbA1c in diabetic patients provides valuable information about the changes occurring in the blood glucose level over the last three months. SOD is considered a first-line Defense against ROS, as it is present in almost all cells and it deals with the most hazardous radicals i.e. Superoxide (O2-). Oxidative stress is in the foreground of diabetes, which increases with an increase in severity of diabetes, keeping these facts in mind the present study was designed to compare the SOD level in type II D.M in Jalgaon district. In the present study, we have got inverse correlation (non-significant correlation) in these two parameters. As the levels of HbA1c increase, there is a decrease in SOD levels, which indicates that as the severity of diabetes increases the levels of SOD decrease.
Pravin Kumar Sonawane, SB Gaikwad, Anshula G, Banker M. Comparative study of HbA1c and superoxide dismutase in type II diabetes mellitus in Jalgaon district. Int J Adv Biochem Res 2021;5(1):39-41. DOI: 10.33545/26174693.2021.v5.i1a.64