International Journal of Advanced Biochemistry Research

Biochem
Journal

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International Journal of Advanced Biochemistry Research

Vol. 3, Issue 1, Part A (2019)

Correlation of liver indices with thrombocytopenia in dengue infected children

Author(s): Dr. Aruna Kumari Bandaru and Divya Sai Vanumu
Abstract: Objective: To evaluate and correlate the early hepatic markers with thrombocytopenia that distinguishes the acute phase of dengue from other febrile illness.
Methods: Study includes 50 controls, 54 other febrile illness and 105 dengue infected children between 3 months to 15 years age group. Liver function tests and platelet count were analyzed.
Results: There was a significant elevation of transaminases, prothrombin time, activated partial thromboplastin time, ammonia with p<0.05 in dengue infection than other febrile illness and controls, but significant decrease in alkaline phosphatase and platelet count. C-reactive protein was significantly raised with P<0.05 in other febrile illness than dengue infection and controls.
Conclusion: During an acute phase of illness, raised aspartate transaminase, activated partial thromboplastin time and platelet count <50000/mm3, C-reactive protein were useful as early markers to differentiate dengue from other febrile illness.
Pages: 15-20  |  859 Views  180 Downloads
How to cite this article:
Dr. Aruna Kumari Bandaru, Divya Sai Vanumu. Correlation of liver indices with thrombocytopenia in dengue infected children. Int J Adv Biochem Res 2019;3(1):15-20. DOI: 10.33545/26174693.2019.v3.i1a.27
International Journal of Advanced Biochemistry Research