International Journal of Advanced Biochemistry Research

Biochem
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International Journal of Advanced Biochemistry Research

Vol. 4, Issue 1, Part A (2020)

Study of random urinary calcium/creatinine ratio as a predictor of preeclampsia in and around Chitradurga

Author(s): Dr. Gaurang K Anandpara, Dr. Basavaraj V Savadi and Dr. Yashkumar Rawal
Abstract: Pre-eclampsia is defined as development of hypertension and proteinuria (>300 mg in 24 hours urine) after 20th week of gestation. The presence of proteinuria remains central to the diagnosis of pre-eclampsia. 24 hours urinary protein measurement is time-consuming and needs more assistance. Spot urinary calcium: creatinine ratio (CCR) has been used to determine the diagnostic accuracy of proteinuria in pre-eclampsia. A case control comparative study was done with women having pre-eclampsia and normal pregnant women admitted in Gynecology department at Basaveshwara Medical College Hospital, Chitradurga according to the criteria. There was a significant negative correlation between calcium: creatinine ratio and 24-hours urinary proteinuria (r= -0.51). Spot urinary calcium: creatinine ratio at cut off value of 0.18 shows 100% sensitivity and 84% specificity. We conclude that the urinary calcium: creatinine ratio should be considered as a potential alternative for 24-hours urine collection for proteinuria in pregnant women to detect pre-eclampsia.
Pages: 12-15  |  603 Views  77 Downloads
How to cite this article:
Dr. Gaurang K Anandpara, Dr. Basavaraj V Savadi and Dr. Yashkumar Rawal. Study of random urinary calcium/creatinine ratio as a predictor of preeclampsia in and around Chitradurga. International Journal of Advanced Biochemistry Research. 2020; 4(1): 12-15. DOI: 10.33545/26174693.2020.v4.i1a.41
International Journal of Advanced Biochemistry Research